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In terms of statistical analysis, various efficacy analyses were performed in all participants that went through the randomization process while safety analysis were used to assess all participants that underwent randomization and were also exposed to one experimental treatment dosage

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Missing one dose reduces cumulative NNMT inhibition slightly but doesn't require compensation

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2.2.1 Oxidative stress and mitochondrial dysfunction METH significantly increases the production of ROS and reactive nitrogen species, overwhelming antioxidant defenses in neurons

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