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Description
The compound has accumulated an impressive body of preclinical research since its discovery

In fact, the high expression of glycogen synthase-1 in RA-FLSs can lead to the excessive accumulation of glycogen and inhibit AMPK expression, leading to the high expression of matrix metallopeptidase (MMP)-1, MMP-9, IL-6, and CCL-2, along with increased proliferation and migration of FLSs

Adv Anat Embryol Cell Biol

Neurology 43: 957962, 1993
