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Biologics, genetically engineered proteins derived from human genes, offer targeted interventions by inhibiting specific components of the immune system associated with inflammation

303 JAK-STAT signaling pathway During the aging process, sustained activation of the JAK-STAT signaling pathway induces the expression of the SASP, promoting cellular senescence and apoptosis, as well as impairing the function of T cells, B cells, and macrophages

The duration of action further distinguishes PE-22-28 from its predecessors

The researchers also found that a protein called pleiotrophin (PTN), seemed to be associated with remyelination in the mouse brains, suggesting that it may inactivate PTPRZ