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Although the precise mechanisms by which BAs modulate immune responses at the maternal-fetal interface remain unclear, emerging clinical evidence links abnormal serum total BA levels to pregnancy complications, including GDM and ICP 289,297,298
Interestingly, pioglitazone exhibited neuroprotective effects in streptozotocin-induced diabetes in rats via modulation of the brain SIRT-1 signaling pathway (Tork et al
Analysis of relative gene expression data using real-time quantitative PCR and the 2 Ct method
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