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Association between diabetes, family history of diabetes, and risk of nonalcoholic steatohepatitis and fibrosis

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Peroxisomal -oxidation degrades very-long-chain fatty acids, with its dysfunction causing lipotoxic mediator accumulation (e.g., ceramides) that induce oxidative stress and aberrant inflammatory signaling (89,90)

The function of EGCG in treating AD has been studied, demonstrating that EGCG participates in a neuroprotective function and is promising to be utilized as a therapeutic drug for treating AD (Fig