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The A peptide generates reactive oxygen species in the presence of transition metals such as copper and iron

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Among them, Acta1, Csrp1, and Tuba1c are involved in the cytoskeleton 51,52,70

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MPO and hypochlorous acid (HOCl) expression were significantly upregulated in NSC-34 cells transfected with the human SOD1 G93A gene, leading to the activation of the MPO/HOCl signaling pathway

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