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SAM homeostasis is regulated by CFIm-mediated splicing of MAT2A
While cytokine spill-over and oxidative stressdriven mechanisms are strongly supported, direct migration of peripheral immune cells into the brain remains less clearly established and appears to depend on disease severity and BBB integrity
FR expression in relation to macrophage polarization warrants further investigations under conditions mimicking inflamed RA synovium
DOI: 10.1111/jnc.14250 10
