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Microglial density greatly increases in WM of aged brains, while remaining stable in gray matter

208 In phase I/II clinical trials, givinostat demonstrated promising efficacy and tolerability in patients with polycythemia vera

Additionally, the relative expression level of the tumor suppressor miRNA miR-145-5p was significantly elevated in the curcumin-treated cells

It also promotes angiogenesis via VEGF upregulation and wound contraction through actin remodeling
