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Description
doi: 10.1097/MOP.0000000000000422

Present knowledge in nutrition: Basic nutrition and metabolism

Results A total of 20 studies, encompassing 44 independent experiments and involving 1019 animals, were included in the analysis

HIF-1 is activated due to blockade of its degradation pathway mediated by low oxygen levels, thereby increasing the expression of target genes, including those encoding glycolytic enzymes and glucose transporters, and increasing lactate secretion 67
