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In turn, lactate-induced H3K18la upregulates SRSF10 expression in macrophages, eventually forming the SRSF10/glycolysis/H3K18la positive feedback loop with tumor cells and promoting M2 macrophage polarization in the tumor microenvironment (TME)

Furthermore, dynamic PDU has a crucial role in the differential diagnosis between psychogenic and the most common form of organic ED, namely vasculogenic ED, in patients of different ages [35]

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