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Description
90 Glutathione synthesis can also be promoted by administration of so-called phase 2 inducers, which stimulate activity of the nrf2 transcription factor to increase expression of a number of antioxidant enzymes, including -glutamylcysteine synthetase, rate-limiting for glutathione synthesis
Significantly, 60% of patients have a 2-fold elevation in activated IgD + CD38 B cells, signifying B cell activation
This is particularly concerning if you already have low glutathione (GSH)
Brain Pathol (Zurich Switzerland)
