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Inhibition of serotonin cargo in platelets by FLX 20 mg/kg or TPH1 inhibitor telotristat reduced colon and pancreatic tumor growth in an established C57BL/6 mice model by increasing CD8 + T accumulation within the tumor [99]
Imagine designing a study around a compound that isn't even what you think it is
Sheikhbahaei et al
3, and Supplementary Data 2, pyruvate kinase, which has two isoforms, PKM1 and PKM2, was prominently upregulated after quinpirole treatment
