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157 ACADSB negatively regulates the expression of GPX4 and glutathione reductase in colon cancer cells, and overexpression of ACADSB increases the concentration of MDA, Fe 2+ and lipid peroxides, inducing cell ferroptosis, and inhibiting the migration and invasion of CRC cells

Filipczak, N., Pan, J., Yalamarty, S

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These findings collectively underscore the multifaceted roles of MMPs in IPF pathogenesis, functioning not merely as ECM modifiers but as dynamic regulators of cellular crosstalk, immune responses, and signaling pathways that collectively drive fibrotic progression