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Description
As a key biomarker in urinary system diseases, TMAO suppresses Megalin expression via PI3K and ERK signaling, activates the MAPK-NLRP3 pathway to induce renal oxidative stress and inflammation, and ultimately leads to renal fibrosis

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doi: 10.1007/s40618-013-0006-0 147 YinLJLuLLinXJWangXH

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