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Specifically, for the first approach to CD44 itself, it is common to develop monoclonal antibodies about CD44 or chemotherapeutic agents that inhibit the binding of CD44 to HA by utilizing sCD44 and specific molecular sizes of HA as inhibitors
In animal models, NAC has been shown to prevent lens opacification and inhibit cataract formation (Wang 2009
Nature 395:288291 Rossier G, Meier C, Bauch C, Summa V, Sordat B, Verrey F, Khn LC (1999) LAT2, a new basolateral 4F2hc/CD98-associated amino acid transporter of kidney and intestine
10.1016/j.ncl.2020.01.001 157 Molina-JimnezM
