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The issue is proceeding without a clear clinical framework for sequencing, inflammation control, and tissue readiness
Unlike GLP-1 agonists such as semaglutide or tirzepatide, which work primarily through appetite suppression, AOD-9604 directly enhances fat metabolism at the cellular level through beta-3 adrenergic receptor modulation

Immune responses can occur in the intima, media, and adventitia of blood vessels
British Journal of Nutrition , 85 (S2), S109S113
