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Nevertheless, some detrimental influences on mammalian health have been observed, like a tumor-stimulating action or deleterious effects on glucose metabolism and lipid profiles

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Two studies also showed the anti-apoptotic effect of melatonin, including a reduction in B-cell lymphoma 2 (Bcl-2) expression and caspase-3 activity [12,13,14,15,16,17,18,19,20,21]

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