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Description
It shares structural similarities and a similar mechanism of action with PGC-1, is widely expressed in mouse tissues, and does not increase in levels in the BAT of mice exposed to cold temperatures (Fig

Elder K, Dixon JM, Blackmur JP, Laurie J

Even on a good day, only about 10-20% might make it through this gauntlet

doi: 10.1186/s13048-025-01683-6 109 PisaniGBaronB
