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Description
An integrative approach to elucidate mechanisms underlying the pharmacokinetic goldenseal-midazolam interaction: application of in vitro assays and physiologically based pharmacokinetic models to understand clinical observations

Its important not to stop the injections prematurely on your own

The mechanism (brain-based, not hormone-dependent) suggests efficacy shouldn't differ dramatically

Connective Tissue Research , 47(2), 81-91
