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Integrated genomics approaches, such as the simultaneous analysis of mutational and RNA expression data, can be used to identify novel cancer driver genes, or uncover critical cancer signalling mechanisms

It also inhibits the NF-B and AP-1 signaling to suppress the expression of pro-inflammatory cytokines IL-1, IL-6, TNF-, and IL-12 ( Supplementary Table 1 )

Cohen TS, Prince A (2012) Cystic fibrosis: a mucosal immunodeficiency syndrome

Statements Data availability statement The original contributions presented in the study are included in the article/supplementary material, further inquiries can be directed to the corresponding author/s