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J Hepatol 74:12481250

After being fed HFD for a total of 16-weeks (an appropriate rodent model of DIO and comparable to human obesity) and reaching pre-arrival body weights (38 g), mice were randomized into balanced control and treatment cohorts (n=9/cohort), with similar group average body weight and standard deviation

A growing body of research suggests low-dose colchicine (generally 0.5 mg per day) may reduce the risk of blood clot-related cardiovascular events such as heart attack and strokeespecially when used in conjunction with other standard cardiovascular medicationsthrough its ability to reduce inflammatory signaling in blood vessels

However, if you experience severe or persistent side effects, it is important to seek medical help