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Metabolism : N-acetylcysteine is deacetylated to cysteine in the liver and vascular endothelium
Its enzymatic function is based on two aspects: its catalytic activity and the auto- S -glutathionylation of GST by itself on Cys47 and Cys10, both of which disturb the subsequent interaction with c-Jun NH 2 -terminal kinase (JNK), resulting in the formation of a GST multimer 30 (Figure 3)
Dragomanova, S.T
While not initially focused on this phenotype, we observed a robust improvement of fur density in FOXO4-DRI-treated XpdTTD/TTD mice
