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However, an unhealthy diet, particularly one high in saturated fats, refined sugars, and processed foods, has been shown to promote oxidative stress by increasing the production of ROS and impairing antioxidant defense systems
10.1016/j.inoche.2023.112006 66 GhobadiM.SalehiS.ArdestaniM

Collectively, these findings establish ferroptosis as a critical contributor to age-related HF and identify the SIRT1GATA4HADHA axis as a potential therapeutic target

Rai J, et al
