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Available from: Specific concomitant medical conditions may raise risk The injections are typically not given when certain complicating medical conditions are present, such as infections, tumors, or bleeding disorders

In: Natural Biopolymers in Drug Delivery and Tissue Engineering , (United Kingdom: Woodhead Publishing) pp

Common side effects include mild discomfort at the injection site, nausea, or dizziness

Indeed, as current in vitro and in vivo toxicity testing methods are mainly used to evaluate the acute and subacute toxicity of metal-based NPs, nanotoxicity testing methods for chronic long-term NPs exposure, which are crucial for predicting chronic toxicity in humans, are still lacking