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Chac1 functions as a GSH-specific -glutamylcyclotransferase, catalyzing the degradation of GSH into 5-oxoproline and Cys-Gly, thereby decreasing intracellular GSH levels (Figure 1A) (17, 19)

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This nuanced position calls for a deeper understanding of BPC-157's origins and therapeutic potential amidst evolving regulatory perspectives

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