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Application as an adjunct to IVF or other fertility treatments is conceivable, for example, as topical treatment to enhance endometrial lining or shield gametes during manipulation

Feng, X., Hao, Y

Nature (1999) 402:65660

High VEGF expression during angiogenesis in breast cancer decreases CD8 T-cell levels via the HMG-bOX ( TOX ) pathway, thereby increasing tumor-cell tolerance to immunotherapy 70 ( Figure 3F )
