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It also significantly improved cardiometabolic parameters, including blood pressure, HbA1c, lipids, and C-reactive protein

Together, these data indicate that two doses of SpFN induced antibodies that targeted a wide range of neutralizing epitopes with cross-sarbecovirus neutralizing activity, while also facilitating Fc effector functions associated with therapeutic and natural protection
This schedule, documented across SURPASS clinical trials, starts at the lowest therapeutic dose and increases by 2.5 mg every four weeks

(2010) The inhibitory effect of ghrelin on sepsis-induced inflammation is mediated by the MAPK phosphatase-1
