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It is possible that some people who develop symptoms of a vitamin B12 deficiency with no clear causative factors may have antibody-negative pernicious anaemia[2]

Thats neither inherently good nor inherently bad

Preclinical cartilage evidence Kwon and Park 2015 in Annals of Clinical and Laboratory Science reported that intra-articular AOD-9604 plus hyaluronic acid in a rabbit knee osteoarthritis model improved cartilage histology and reduced lameness compared with hyaluronic acid alone

Still, imbalances can occur if you are dehydrated due to illness, extreme heat, or when you engage in a fasting exercise
