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Without surface modification, most nanoparticlesincluding agar-based systemsare restricted to peripheral circulation and are rapidly cleared by the reticuloendothelial system

Likewise, this notion will be further supported by the detection of expression of particular genes ( Vegfr2, Src, Nos2, Nos1, Nos3, Akt1, Kras, Mapk1, Srf, Foxo1, Nfkb1, and Egr1 ) in hippocampal tissue

The tumor volume was calculated as follows: V (mm 3 ) = (LW 2 ) / 2 AP probe-net treatment and pathological detection Before treatment, the weight of each mouse and the size of the tumor were measured, and each mouse was photographed

Images were acquired with a Leica SP8 confocal microscope