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At progression, the metabolic profile indicates chronic BM niche remodeling: sustained CD38 blockade only partially limits ADO generation above immunoregulatory thresholds, while increased ADA/CD26 activity accelerates ADO deamination and shifts purine flux toward INO

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AHA Coding Clinic (Recent Guidance) The following guidance from AHA Coding Clinic (American Hospital Association) is directly relevant to adjuvant therapy coding

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