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In small studies, most patients with chronic knee pain or chronic bladder pain reported major improvement after BPC157 treatment

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The addition of semaglutide to this already high-risk group showed further b12 decline, but whether this represents a medication effect, dietary changes from additional appetite suppression, or natural progression of post-surgical deficiency remains unclear

Kuzminski AM, Del Giacco EJ, Allen RH, Stabler SP, Lindenbaum J