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Long-chain Omega-3 fatty acids supplementation and cognitive performance throughout adulthood: A 6-month randomized controlled trial

In response to oxidative stress, NRF2 dissociates from KEAP1, translocates to the nucleus, and activates genes encoding antioxidant enzymes (e.g., superoxide dismutase SOD) and glutathione synthesis enzymes, reducing reactive oxygen species (ROS) and mitigating oxidative damage ( Therapeutic interventions targeting redox imbalance in fibromyalgia Currently, there is a lack of randomized controlled trials (RCTs) directly evaluating redox-modulating interventions targeting the central nervous system (CNS) in fibromyalgia

[DOI] [PMC free article] [PubMed] [Google Scholar] 36.Yui K., Sato A., Imataka G

The model formula was: TMAO ~ (Time + Time) * Group * Intake + (1 + Time | ID), with random intercepts and random slopes for time at the participant (ID) level