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The interest in natural extracts has increased in the pharmaceutical, cosmetic and food industries due to their bioactive properties, claimed by the quickly growing market of antioxidant-containing healthy foods

The origin of cytosolic NADH is from the pathway of glycolysis and the electrons in cytosolic NADH are transported into the mitochondria via the actions of the malate-aspartate shuttle (to mitochondrial NADH) or by the glycerol phosphate shuttle (to mitochondrial FADH 2 )

Tumor volume was calculated using the formula: 1/2 length width

3 that all tumor cells have equal capacity to enter and exit the DTP state to survive therapy