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doi: 10.2147/DDDT.S280802
Diabetic neuropathy and neuropathic pain: a (con)fusion of pathogenic mechanisms

developed a multiple heart-cutting achiralchiral 2D-LC-MS method that enables simultaneous oxylipin quantification and determination of stereochemistry

Under oxidative stress, excessive ROS emissions lead to mitochondrial damage, and loss or defects in mitochondrial energy production can enhance metabolic processes in the tricarboxylic acid (TCA) cycle, ETC, exacerbating ROS release and reducing antioxidant enzymes [81,82,83]
