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In mesenchymal TNBC which is a subcategory of TNBC and is featured with high rates of invasion and metastasis according to Lehmann BD work [57, 114], stable deletion of CD44 with shRNA vectors restrained proliferation, colony formation and invasion of SUM159, MDA-MB-436 and MDA-MB-231 [115]

(2022), who showed Nrf2 regulates GSH synthesis via HO-1/GPX4, and our findings extend this: chronic Nrf2 suppression in mid-late SAE disrupts GSH homeostasis (impairing synthesis/recycling) and diminishes GPX4-mediated anti-lipid peroxidation, promoting ferroptosis

[15] It is important for patients prone to hypoglycemia to monitor their blood glucose and recognize these symptoms

We then used ProteinMPNN [33] to predict which sequences of amino acids would preferably fold into the backbone geometries designed with RFD