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Targeting aerobic glycolysis: 3-bromopyruvate as a promising anticancer drug

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Miratashi Yazdi SA, Abbasi M, Miratashi Yazdi SM

In vitro, astrocytes derived from induced pluripotent stem cells obtained from patients with FTD-MAPT showed hypertrophy, elevated GFAP protein levels, disease-associated changes in TAU expression, increased vulnerability to oxidative stress, and protein ubiquitination 231
