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By inhibiting NNMTs consumption of SAM, 5-Amino-1MQ may affect the methylation status of various cellular targets
On the other hand, interestingly, natural log-transformed high-sensitivity C-reactive protein (HS-CRP) was significantly elevated in the low IGF-1 group ( 0.16 [ 0.62, 0.01] vs

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Another possibility is that obesity could lower serum vitamin B12 levels through decreased dietary intake or absorption, increased catabolism, and sequestration in adipose tissue, or changes in the gut microbiota profiles which could affect the metabolism of vitamin B12
