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Moreover, because only a single tumor region per patient was analyzed at each time point, spatial intratumoral heterogeneity may not have been fully captured, which could partially explain the apparent gain or loss of certain variants observed before and after NAC

The protein concentration was determined from the supernatant obtained after 15 min at 4 C and 100.000 g by Bradford assay

The association between iron dysregulation, oxidative stress and lipid peroxidation central to ferroptosis suggests that this form of cell death could be integral to the pathophysiology of schizophrenia

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