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It works at the cellular level, helping neutralize melanin production, which can reduce dark spots and dullness over time

[DOI] [PMC free article] [PubMed] [Google Scholar] 114.Gallegos-Castorena S., Martnez-Avalos A., Mohar-Betancourt A., Guerrero-Avendao G., Zapata-Tarrs M., Medina-Sansn A

demonstrated the efficacy of andrographolide, a diterpene lactone, in protecting the blood-brain barrier by inhibiting the CypA-NF-B-MMP-9 pathway, highlighting its dual anti-inflammatory and neuroprotective effects (Zhou X et al., 2024)

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