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In fact, perhexiline decreased multiple genes expression, including ABCB4, ABCB11, ABCC3, ABCG5, adaptor related protein complex 1 subunit sigma 1 (AP1S1), solute carrier family 10 member 1 (SLC10A1), solute carrier organic anion transporter family, member 1a1 (SLCO1A1), and transgelin (TAGLN), and increased multiple genes expression, including ABCB2, N -acylsphingosine amidohydrolase 1 (ASAH1), asparagine synthetase (ASNS), activating transcription factor 4 (ATF4), ATF6, DEPP autophagy regulator 1 (DEPP1), eukaryotic translation initiation factor 4E (EIF4E)/EIF4E binding protein 1 (EIF4EBP1), FABP1, fibronectin type III domain containing 4 (FNDC4), glycerophosphodiester phosphodiesterase domain containing 3 (GDPD3), hepsin (HPN), inhibin subunit beta E (INHBE), potassium voltage-gated channel subfamily H member 2 (KCNH2), lanosterol synthase (LSS), nuclear receptor subfamily 0 group B member 2 (NROB2), nuclear protein 1, transcriptional regulator (NUPR1), serpin family A member 3 (SERPINA3), transmembrane serine protease 2 (TMPRSS2), WD repeat domain, phosphoinositide interacting 1 (WIPI1) [132,133,134,135,136,137]

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