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Description
PregS potentiates recombinant NMDARs with GluN1-1a/GluN2B through a steroid modulating domain in GluN2B that also modulates tonic proton inhibition and is pH independent
Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities

While studies confirm their potential, they have very different track records

doi: 10.1001/archopht.1993.01090060049022