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Anyone who loves clinical cases will surely enjoy reading them, because, although they are unfortunately sad (and we wish each of them the best outcome and a speedy recovery), the number and variety of symptoms, as well as the uncertainty of their onset and how they affect each person, is fascinating

In HTN, chronic activation of Ang II and NOXs overwhelms this system, leading to Nrf2 dysfunction or exhaustion, which exacerbates ROS accumulation, endothelial dysfunction, and vascular remodeling

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Involvement of reactive oxygen species and nitric oxide radicals in activation and proliferation of rat hepatic stellate cells