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Deferoxamine, the first FDA-approved drug in 1968 (Parker et al., 2023), is administered via intravenous (IV) or intramuscular (IM) injection due to its poor oral bioavailability, which is one of the most significant limitations of the DFO treatment (Entezari et al., 2022)

Biomimetic nanomaterials refer to nanomaterials designed and synthesized by mimicking the structures, functions, or mechanisms found in nature (Gareev et al., 2022
