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1 The presence of hypoxia has greater significance for single-dose fractions used in the treatment of certain primary tumors and metastases and is less important for fractionated radiotherapy, where reoxygenation occurs between fractions

HDAC inhibitors, such as valproic acid and vorinostat, have been explored as potential treatments for Alzheimer's, Parkinson's, and Huntington's diseases due to their ability to enhance gene expression related to neuronal survival and synaptic plasticity

Bueno Lled J, Torregrosa-Gallud A

This article was supported by 345 talent project plan of Shengjing Hospital of China Medical University