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The widespread and extensive use of gutkha, khaini, and zarda (cheaper and more accessible than cigarettes) has rendered smokeless tobacco an endemic affliction across rural and peri-urban India (198)
Mucus functions in the lung as a critical defense mechanism [26, 27]

Hence, more research is needed, although, overall, AP-1 inhibition, just like NF-B, appears to be a common mechanism for sulforaphane as an anti-inflammatory compound

285 According to Salari et al
