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These events lead to inhibition of Axin-mediated -catenin phosphorylation and thereby to the stabilization of -catenin, which accumulates and travels to the nucleus to form complexes with TCF/LEF and activates Wnt target gene expression (Figure 1b)
E.PoulsenH
Behaviour is a functional indicator of the net sensory, motor, and integrative processes in the central and peripheral nervous systems, which are thought to be more sensitive in detecting toxicity (Mitchell et al., 1982)
[DOI] [PMC free article] [PubMed] [Google Scholar] 182.Kang C, Xu Q, Martin TD, Li MZ, Demaria M, Aron L, et al
