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Intermittent fasting from dawn to sunset for 4 weeks induces key regulatory proteins of insulin signaling and improves insulin resistance Four-week intermittent fasting induced key regulatory proteins of insulin signaling, including VPS8, POLRMT and IGFBP5 at the end of 4th week during 4-week intermittent fasting and PRKCSH 1 week after 4-week intermittent fasting

Nuclear gene expression reprogramming: metabolism, antioxidation and mitochondrial biosynthesis Mitochondria serve not only as energy hubs but also as sources of diverse metabolic signals that modulate nuclear gene transcription and translation via retrograde signaling, coordinating metabolism and transcription [228]

294FosterGEHanlyPJAhmedSBBeaudinAEPialouxVPoulinMJ