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Oxidative GPX4 inactivation is obviously a crucial step in sperm maturation
The major advantage of this approach is that small molecules have a considerable higher bioavailability compared to antibodies, dominant-negative receptors and antisense oligonucleotides
doi: 10.1158/1535-7163.MCT-09-0499 [DOI] [PubMed] [Google Scholar] 223
A standard view of systems or network biology (for example, Kell (444) and Kell & Knowles (445) ) develops these ideas in four stages
