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The primary benefits of employing nanocarriers in the treatment of ocular illnesses include enhanced bioavailability of topical administration, controlled release, precise targeting of ocular tissues, and better therapeutic efficacy [365, 366]

Notably, BNIP3 was upregulated in NIX knockout mice, suggesting a compensatory mechanism for receptor-mediated mitophagy under hypoxia
Notably, AIM2 confers resistance even in treatment-nave cells, positioning it as both a biomarker and a therapeutic target
