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The narrative format was selected to accommodate heterogeneous evidence spanning preclinical mechanisms, clinical trials, and translational barriers where systematic synthesis would be inappropriate
doi: 10.1016/j.freeradbiomed.2012.03.019
The following sections detail the interconnected mechanisms underlying NO-induced neurotoxicity
Smoking and alcohol consumption are known to increase oxidative stress, deplete antioxidant reserves, and impair sperm function
